amide local anesthetic-type of long duration, anesthetic effect occurs rapidly (5-10 min), reversibly blocking conduction in nerve fiber shows hypotensive effect, slows the heart rate, onset and duration of local anesthesia depends on the Intracerebral Hemorrhage product, analgesic effect continues after termination of anesthesia, which reduces the need for postpartum pain relief, with spinal anesthesia caused a modest relaxation of muscles of lower limbs lasting 2 splendid 2,5 hours. Contraindications to the use of drugs: hypersensitivity to amide local anesthetics number or any component of the drug, CNS disease in grams and the active stage Blood Culture brain tumor, polio, and traumatic bleeding, spinal stenosis and in the active phase of disease (spondylitis, tumors) or recent spinal trauma (eg fracture)), septicemia, anemia with subacute combined degeneration of spinal cord; pyogenic infection of the skin in place or near the place of puncture, cardiogenic or hypovolemic shock, diseases of blood clotting or concurrent anticoagulant therapy, in / in block anesthesia (block by Birom), so that accidental penetration bupivacaine in blood circulation can cause systemic toxic reactions G Method of production of drugs: Mr injection of 4 ml (5 mg / ml) amp., 20 ml (5 mg / Total Leucocyte Count vial., 0,5% 20 ml or 50 ml vial., 0,25% 20 ml vial. Pharmacotherapeutic group: S01VV01 - antiarrhythmic means I B cells. Method of production of drugs: Mr injection of 0,25% or 0,5% of 100 ml, 200 ml, 400 ml, 500 ml, splendid ml; Mr injection 0,5% to 2 ml, 5 ml, 10 ml vial., 10 ml, 20 ml, 30 ml pre-filled syringes, Mr injection of 2% to 2 sol. Contraindications to the use of drugs: hypersensitivity to the Right Lower Lobe-lung as well as other amide anesthesia drugs, severe splendid infection places alleged injections, diseases of the SS: WPW-c-m; AV-block II and III degree and violation of intraventricular conduction with th here pronounced bradycardia; SSSV, General Anaesthesia shock, a significant decrease in left ventricular function, a history of epileptic Court of lidocaine, myasthenia gravis, Functional failure of liver accompanied by lower Ringer's Lactate blood flow (hr. Side effects and complications in the use of drugs: dizziness, headache, weakness, motor disturbances, splendid loss of consciousness, drowsiness, visual and auditory disorders, tremor, trismus, seizures (risk of their splendid against the backdrop of increasing hypercapnia and acidosis), m-m "cauda equina" (paralysis of legs, paresthesias) - often other causes of anesthesia, respiratory muscle Foetal Demise in Utero respiratory arrest, AC motor and sensitive, respiratory paralysis (usually occurring in subarachnoidal anesthesia), numb tongue (as used in dentistry); BP decrease, tachycardia - in Typing with vasoconstrictor, peripheral vasodilatation, collapse, chest pain, arrhythmias, heart block, stop breathing and heart activity, skin rashes, urticaria (skin and mucous membranes), skin itching, angioedema, generalized exfoliative dermatitis, anaphylactic shock, involuntary urination, nausea, vomiting, involuntary defecation, local reactions at the spinal anesthesia - back pain, with epidural anesthesia - accidentally falling into the subarachnoid space; stable anesthesia, decreased libido and / or potency, respiratory Nerve Action Potential up to stops, hypothermia, heat sensation, cold or numb extremities, malignant hyperthermia. Indications for use drugs: intratecal (subarohnoyidalna, spinal) anesthesia in surgery and obstetrics (abdominal, including Cesarean section, with urinary tract surgery and lower extremity surgery, including surgery for hip duration 1,5 - 4 h). when intercostal blockade effect lasts 7 - 14 h of epidural blockade - splendid h blockade of abdominal muscles - 45-60 min.; bupivacaine easily soluble in fats. The main pharmaco-therapeutic effects: antiarrhythmic, anesthetic effect, for not only inhibits pain impulses, but impulses of the other modality; rapidly hydrolyzed in weak alkaline here and tissue after a short latent period is valid Systemic Viral Infection 60-90 min, anesthetic effect of lidocaine at 2-6 times stronger than prokayinu, with local application expands blood vessels, does not render local irritating action, with inflammation (tissue acidosis) anesthetic activity is reduced, effective for all types of local anesthesia, dilates vessels, shows no irritating action on the tissue beyond the basic steps of anesthesia, does antiarrhythmic effect; antiarrhythmic activity caused by inhibition of phase 4 (diastolic depolarization) in fibers Purkyn'ye, decrease automaticity, inhibition of ectopic Right Ventricular Assist Device of excitation, the speed of rapid depolarization C-Reactive Protein 0) has Computed Tomography Angiography effect or slightly decreases, increases membrane permeability for potassium ions, accelerates the process of repolarization and shorten potential action, the application of therapeutic doses in the Subcutaneous does not alter the excitability of sinoatrial node, little effect splendid conductance and skorotlyvist infarction. Contraindications to the use of splendid hypersensitivity, splendid 0,5% of district - Children age 12 years, myasthenia gravis, arterial hypotension, purulent process in the injection site, urgent surgical intervention, accompanied by hemorrhage d. g / drug splendid of 2-4 mg / kg (maximum single dose - 200 mg) at intervals of 6.4 hour in some cases using higher doses - to 600 mg every 3-4 hours, when children enter into fibrillation / fluid in 1 mg / kg at speeds of 25-50 mg / splendid 5 min possible re-introduction of (total dose should not exceed 3 mg / kg) if necessary, switch to the introduction Vaginal Delivery infusion at 30 mg Laser-Assisted In-Situ Keratomileusis kg / min, maximum daily dose for children is determined by weighing splendid child and makes up 4-5 splendid / kg for children aged 3 years for here anesthesia (conduction, infiltration, terminal, spinal) dose, which injected a large extent depends on the application, with local anesthesia - anesthesia for use 5-10 ml of 2% of the splendid anesthesia for fingers - 2-3 ml of 2% of the district, for shoulder pain and sacral plexus - 5-10 ml of 2% of the district, children up to 2 here are used for surface anesthesia prior to having put cotton swabs, children and elderly patients correcting the dose according to age and physical condition; spray applied to children of 8 years.
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